3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[91713-46-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-5-o-ditoluoyl-6-chloropurine-9-β-d-deoxyriboside.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C)C=C1)O[C@H]2C[C@H](N3C(N=CN=C4Cl)=C4N=C3)O[C@@H]2COC(C5=CC=C(C)C=C5)=O
Molecular Formula
C26H23ClN4O5
Molecular Weight
506.94
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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