Guaiacol
Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[1].
Product Specifications
CAS Number
90-05-1
Product Name Alternative
2-Methoxyphenol
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
COX; Endogenous Metabolite; NF-κB
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Guaiacol.html
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL|H2O : 37.5 mg/mL (ultrasonic)
Smiles
OC1=CC=CC=C1OC
Molecular Formula
C7H8O2
Molecular Weight
124.14
Precautions
H302, H315, H319
References & Citations
[1]Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27 (2) :801-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
COX-2; NF-κB
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