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DOTA-​NHS-ester

DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1].

Product Specifications

UNSPSC

12352203

Hazard Statement

H315, H319

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dota-nhs-ester.html

Purity

97.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(ON1C(CCC1=O)=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2

Molecular Formula

C20H31N5O10

Molecular Weight

501.49

Precautions

H315, H319

References & Citations

[1]Hoppmann S, et al. Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting.Bioconjug Chem. 2011 Mar 16;22 (3) :413-2

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128890/DOTA-NHS-ester-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128890/DOTA-NHS-ester-SDS-MedChemExpress.pdf

Scientific Category

ADC Related

Clinical Information

No Development Reported

CAS Number

[170908-81-3]

Available Sizes

Curated Selection

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