BMS-189664

BMS-189664 is a potent, selective, and orally active reversible inhibitor of a-thrombin, with an IC50 of 0.046 μM. BMS-189664 can be used for arterial and venous thrombosis research[1].

Product Specifications

CAS Number

162166-80-5

UNSPSC

12352005

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bms-189664.html

Smiles

O=C(N1CCC[C@H]1C(NCC2CCN(C(N)=N)CC2)=O)[C@H](NS(C)(=O)=O)CC3=CC=CC=C3

Molecular Formula

C22H34N6O4S

Molecular Weight

478.61

References & Citations

[1]Das J, et al. Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664. Bioorg Med Chem Lett. 2002 Jan 7;12 (1) :45-9.