O-Phthaldialdehyde (OPA)

<strong>o-Phthaldialdehyde (OPA)</strong>_x000D_ <strong>Catalog number:</strong> B2011262_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 134.1 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> o-Phthaldialdehyde_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhang Q, Zhang Y, Li X. Ortho-Phthalaldehyde (OPA)-based chemoselective protein bioconjugation and peptide cyclization Methods Enzymol. 2020;639:237-261._x000D_ 2: Sadarangani M, Pollard AJ, Gray-Owen SD. Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria FEMS Microbiol Rev. 2011 May;35(3):498-514._x000D_ 3: Gray-Owen SD. Neisserial Opa proteins: impact on colonization, dissemination and immunity Scand J Infect Dis. 2003;35(9):614-8._x000D_ 4: Wang WD, Kang WB, Zhou XQ, Yao GF, Wang XJ. Mitochondrial protein OPA mediates osteoporosis induced by radiation through the P38 signaling pathway Eur Rev Med Pharmacol Sci. 2018 Dec;22(23):8091-8097._x000D_ 5: Dehio C, Gray-Owen SD, Meyer TF. The role of neisserial Opa proteins in interactions with host cells Trends Microbiol. 1998 Dec;6(12):489-95._x000D_ 6: Toma C, Bâlteanu VA, Tripon S, Trifa A, Rema A, Amorim I, Pop RM, Popa R, Catoi C, Taulescu M. Exogenous Jaagsiekte Sheep Retrovirus type 2 (exJSRV2) related to ovine pulmonary adenocarcinoma (OPA) in Romania: prevalence, anatomical forms, pathological description, immunophenotyping and virus identification BMC Vet Res. 2020 Aug 17;16(1):296._x000D_ 7: Alcott AM, Werner LM, Baiocco CM, Belcher Dufrisne M, Columbus L, Criss AK. Variable Expression of Opa Proteins by Neisseria gonorrhoeae Influences Bacterial Association and Phagocytic Killing by Human Neutrophils J Bacteriol. 2022 Apr 19;204(4):e0003522._x000D_ 8: Sadarangani M, Hoe CJ, Makepeace K, van der Ley P, Pollard AJ. Phase variation of Opa proteins of Neisseria meningitidis and the effects of bacterial transformation J Biosci. 2016 Mar;41(1):13-9._x000D_ 9: Saeki H, Kawashima M, Sugaya S, Oshiden K, Tsubouchi H. Efficacy and safety of topical OPA-15406, a new phosphodiesterase 4 inhibitor, in Japanese patients with atopic dermatitis for 8 weeks: A phase 2, randomized, double-blind, placebo-controlled study J Dermatol. 2019 Aug;46(8):672-679._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31713267">10: Saeki H, Baba N, Oshiden K, Abe Y, Tsubouchi H. Phase 2, randomized, double-blind, placebo-controlled, 4-week study to evaluate the safety and efficacy of OPA- 15406 (difamilast), a new topical selective phosphodiesterase type-4 inhibitor, in Japanese pediatric patients aged 2-14 years with atopic dermatitis J Dermatol. 2020 Jan;47(1):17-24. </a>_x000D_ _x000D_ <strong>Products Related to o-Phthaldialdehyde (OPA) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>