ADC Control Human IgG1-Deruxtecan (DAR 4)
Product Specifications
UNSPSC Description
ADC Control Human IgG1-Deruxtecan (DAR 4) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E)[1].
Target Antigen
Antibody-Drug Conjugates (ADCs); Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/adc-control-human-igg1-deruxtecan-dar-4.html
Smiles
[ADC Control Human IgG1-Deruxtecan (DAR 4)]
References & Citations
[1]Matilde Bocci, et al. In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment. J Control Release. 2024 Mar:367:779-790.
Shipping Conditions
Dry Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164152/ADC-Control-Human-IgG1-Deruxtecan-DAR-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164152/ADC-Control-Human-IgG1-Deruxtecan-DAR-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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