4-Phenyl-1H-1,2,3-triazole
4-Phenyl-1H-1,2,3-triazole is an IDO1 inhibitor (IC50: 60 μM) . 4-Phenyl-1H-1,2,3-triazole can be used for cancer research[1].
Product Specifications
CAS Number
[1680-44-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-phenyl-1h-1-2-3-triazole.html
Purity
99.35
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C1(C2=CC=CC=C2)=CN=NN1
Molecular Formula
C8H7N3
Molecular Weight
145.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Röhrig UF, et al. Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition. J Med Chem. 2012 Jun 14;55 (11) :5270-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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