Chemerin-9, mouse
Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM) . Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes (IC50 = 3.3 nM) . Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis[1][2][3].
Product Specifications
CAS Number
686324-96-9
Product Name Alternative
Chemerin148–156, mouse
UNSPSC
12352209
Target
Chemerin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chemerin-9-mouse.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@H](CO)C(O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O
Molecular Formula
C51H68N10O12
Molecular Weight
1013.15
References & Citations
[1]Shimamura K, et al. Identification of a stable chemerin analog with potent activity toward ChemR23. Peptides. 2009 Aug;30 (8) :1529-38.|[2]Lei Z, et al. Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-Induced Object Memory Impairment in Mice. Biol Pharm Bull. 2020 Feb 1;43 (2) :272-283.|[3]Sato K, et al. Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis. Clin Sci (Lond) . 2019 Aug 20;133 (16) :1779-1796.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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