Cis-5-Dodecenoic acid

Cis-5-Dodecenoic acid is an inhibitor of COX-I and COX-II with anti-inflammatory activity. cis-5-Dodecenoic acid reduces prostaglandin synthesis by inhibiting COX enzyme activity and is involved in the fatty acid -β oxidative metabolic pathway. The metabolic rate of cis-5-Dodecenoic acid is significantly lower than that of saturated fatty acids. cis-5-Dodecenoic acid can be used in the research of anti-inflammation, fatty acid metabolism mechanisms and related physiological and pathological processes[1][2].

Product Specifications

CAS Number

[2430-94-6]

UNSPSC

12352211

Hazard Statement

H314

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cis-5-dodecenoic-acid.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCC/C=C\CCCC(O)=O

Molecular Formula

C12H22O2

Molecular Weight

198.30

Precautions

H314

References & Citations

[1]Henry GE, et al. Antioxidant and cyclooxygenase activities of fatty acids found in food. J Agric Food Chem. 2002 Apr 10;50 (8) :2231-4.|[2]Tserng KY, et al. Comparison of metabolic fluxes of cis-5-enoyl-CoA and saturated acyl-CoA through the beta-oxidation pathway. Biochem J. 1995 Apr 1;307 (Pt 1) (Pt 1) :23-8