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CpG ODN 10101 (sodium)

CpG ODN 10101 sodium, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 sodium is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2 (VQLRIRVAVIRA-NH2) . CpG ODN 10101 sodium induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 sodium has antiviral and immunomodulatory properties that can influence chronic infection with HCV[1][2].

Product Specifications

Product Name Alternative

ODN 10101 (sodium)

UNSPSC

12352208

Target

Toll-like Receptor (TLR)

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cpg-odn-10101-sodium.html

Purity

98.84

Solubility

10 mM in H2O

Smiles

[CpGODN10101(sodium)]

Molecular Weight

7185.00

References & Citations

[1]John G McHutchison, et al. Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus. Hepatology. 2007 Nov;46 (5) :1341-9.|[2]Jason Kindrachuk, et al. A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity. Vaccine. 2009 Jul 23;27 (34) :4662-71.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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