Norartocarpetin
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].
Product Specifications
CAS Number
520-30-9
UNSPSC
12352005
Target
Apoptosis; MAPKAPK2 (MK2) ; Raf; Ras; Tyrosinase
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/norartocarpetin.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2O)OC3=CC(O)=CC(O)=C13
Molecular Formula
C15H10O6
Molecular Weight
286.24
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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