(S) -Mirtazapine

(S) -Mirtazapine ((S) -Org3770) is a S (+) -enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S) -Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S) -Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].

Product Specifications

CAS Number

[61337-87-9]

Product Name Alternative

(S) -Org3770; (S) -6-Azamianserin

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-mirtazapine.html

Purity

99.76

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CN1C[C@]2([H])C3=CC=CC=C3CC4=CC=CN=C4N2CC1

Molecular Formula

C17H19N3

Molecular Weight

265.35

References & Citations

[1]Muth-Selbach U, et al. Racemic intrathecal mirtazapine but not its enantiomers acts anti-neuropathic after chronic constriction injury in rats. Brain Res Bull. 2009 Apr 6;79 (1) :63-8.