Dihydrexidine (hydrochloride)
Dihydrexidine hydrochloride (DAR-0100 hydrochloride) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist, with an IC50 of 10 nM for D1 receptor. Dihydrexidine hydrochloride exhibits potent antiparkinsonian activity[1][2][3][4]. Dihydrexidine hydrochloride can stimulate YAP phosphorylation[5].
Product Specifications
CAS Number
137417-08-4
Product Name Alternative
DAR-0100 (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dihydrexidine-hydrochloride.html
Purity
98.89
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)
Smiles
OC1=C(O)C=C(CC[C@]2([H])[C@]3([H])C4=C(C=CC=C4)CN2)C3=C1.Cl
Molecular Formula
C17H18ClNO2
Molecular Weight
303.78
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
D1 Receptor
Available Sizes
Frequently Asked Questions
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