Clocortolone pivalate

Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis[1].

Product Specifications

CAS Number

[34097-16-0]

UNSPSC

12352211

Hazard Statement

H360, H372

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/clocortolone-pivalate.html

Purity

99.93

Solubility

DMSO : 10 mg/mL (ultrasonic) |Ethanol : ≥ 12.5 mg/mL

Smiles

Cl[C@@]1([C@]2(C=C3)C)[C@](C[C@H](F)C2=CC3=O)([H])[C@@]4([H])[C@@](C)([C@@H](C(COC(C(C)(C)C)=O)=O)[C@H](C)C4)C[C@@H]1O

Molecular Formula

C27H36ClFO5

Molecular Weight

495.02

Precautions

H360, H372

References & Citations

[1]Kircik LH, et al. The treatment of inflammatory facial dermatoses with topical corticosteroids: focus on clocortolone pivalate 0.1% cream. J Drugs Dermatol. 2012 Oct;11 (10) :1194-8.