BMS-960

BMS-960 is a potent and selective S1P1 receptor agonist containing isoxazole, which can be used in the research of immune diseases and vascular diseases[1].

Product Specifications

CAS Number

[1265323-40-7]

UNSPSC

12352005

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bms-960.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1CN(C[C@@H](O)C2=CC=C(C3=NOC(C4=C(C(F)(F)F)C(C5=CC=CC=C5)=NO4)=N3)C=C2)CCC1)O.[H]Cl

Molecular Formula

C26H24ClF3N4O5

Molecular Weight

564.94

References & Citations

[1]Hou X, et al. Regioselective epoxide ring opening for the stereospecific scale-up synthesis of BMS-960, a potent and selective isoxazole-containing S1P1 receptor agonist[J]. Organic Process Research & Development, 2017, 21 (2) : 200-207.