Dexamethasone 9,11-epoxide

Dexamethasone 9,11-epoxide is an intermediate. Dexamethasone 9,11-epoxide can be used in the preparation of Dexamethasone (HY-14648) . Dexamethasone 9,11-epoxide can be used in the research of inflammatory and immune diseases[1].

Product Specifications

CAS Number

[24916-90-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Dexamethasone_9,11-epoxide.html

Purity

99.59

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

C[C@@]12[C@](C(CO)=O)(O)[C@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@]3(O5)[C@]5([H])C2)=O

Molecular Formula

C22H28O5

Molecular Weight

372.45

Precautions

H315, H319, H335

References & Citations

[1]Du, et al. Method for preparing dexamethasone intermediate product through one-step microbial fermentation and transformation. CN106520896A. China. 2016-12-21. |[2]Алексей Витальевич Казанцев, et al. Method of obtaining 11beta, 17 alpha, 21-trihydroxy-16alpha-methyl-9alpha-fluoropregna-1,4-diene-3,20-dione (dexamethazone) from phytosterol. RU2532902C1. Russia. 2013-07-12.