BAY 73-6691
BAY 73-6691 ((R) -BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor[1].
Product Specifications
CAS Number
[794568-92-6]
UNSPSC
12352005
Hazard Statement
H300, H315, H319, H335, H413
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/BAY_73-6691.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1C2=C(N(C3=CC=CC=C3Cl)N=C2)NC(C[C@@H](C)C(F)(F)F)=N1
Molecular Formula
C15H12ClF3N4O
Molecular Weight
356.73
Precautions
H300, H315, H319, H335, H413
References & Citations
[1]Li J, et al. Protective effects of BAY 73-6691, a selective inhibitor of phosphodiesterase 9, on amyloid-β peptides-induced oxidative stress in in-vivo and in-vitro models of Alzheimer's disease. Brain Res. 2016 Jul 1;1642:327-335.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE9
Available Sizes
Curated Selection
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