6Ckine/CCL21A, Mouse (sf9, His)
6Ckine/CCL21A Protein, Mouse (sf9, His) is a homeostatic lymphoid chemokine that contributes to the entry of T cells and dendritic cells into the lymphoid T-zone. It acts through chemokine receptors CCR7 and CXCR3 to promote fibrogenic and inflammatory cytokine production. 6Ckine/CCL21 Protein, Mouse (sf9, His) is a recombinant mouse 6Ckine/CCL21A (S24-G133) expressed by Sf9 insect cells with a his tag at the C-terminus[1].
Product Specifications
Product Name Alternative
6Ckine/CCL21A Protein, Mouse (sf9, His), Mouse, Sf9 insect cells
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/6ckine-ccl21-protein-mouse-sf9-his.html
Molecular Formula
18829 (Gene_ID) P84444 (S24-G133) (Accession)
Molecular Weight
Approximately 13.5 kDa
References & Citations
[1]Balsam Rizeq, et al. The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression. Cancers (Basel) . 2020 Apr 23;12 (4) :1036.|[2]Knut Biber, et al. Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development. EMBO J. 2011 May 4;30 (9) :1864-73.|[3]Michael Hirth, et al. CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients. Gastroenterology. 2020 Aug;159 (2) :665-681.e13.
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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