Carbinoxamine-d6 (maleate)

Carbinoxamine-d6 (maleate) is the deuterium labeled Carbinoxamine maleate salt. Carbinoxamine maleate salt is a histamine H1 receptor antagonist.

Product Specifications

UNSPSC

12352005

Target

Histamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C(C2=NC=CC=C2)OCCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C1.O=C(O)/C=C\C(O)=O

Molecular Formula

C20H17D6ClN2O5

Molecular Weight

412.90

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Harikrishnan A, et al. The cooperative effect of Lewis pairs in the Friedel-Crafts hydroxyalkylation reaction: a simple and effective route for the synthesis of (±) -carbinoxamine. Org Biomol Chem. 2015 Mar 28;13 (12) :3633-47.