p53 Activator 12
Product Specifications
UNSPSC Description
p53 Activator 12 (compound 510B) is a potent p53 activator. p53 Activator 12 binds to mutant p53 and restores the ability of the p53 mutant to bind DNA[1].
Target Antigen
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-12.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)CN1C2=CC=CC(N[C@H]3[C@H](CN(CC3)C)C)=C2C=C1C4=NOC(CNC(C5=CN(N=C5)C(C)(C)C)=O)=N4
Molecular Weight
572.63
References & Citations
[1]Binh Vu, et al. methods and compounds for restoring mutant p53 function. US20240043436.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158151/p53-Activator-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158151/
Clinical Information
No Development Reported
CAS Number
2746374-04-7
Curated Selection
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