Cyclic AMP

Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes[1][2][3].

Product Specifications

CAS Number

[60-92-4]

Product Name Alternative

Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cAMP.html

Purity

99.95

Solubility

0.1 M NaOH : 50 mg/mL (ultrasonic; adjust pH to 6 with NaOH)

Smiles

NC1=C2N=CN([C@@H]3O[C@]4([H])COP(O)(O[C@@]4([H])[C@H]3O)=O)C2=NC=N1

Molecular Formula

C10H12N5O6P

Molecular Weight

329.21

Precautions

H302, H315, H319, H335

References & Citations

[1]G M Fimia, et al. Cyclic AMP signaling. J Cell Sci. 2001 Jun;114 (Pt 11) :1971-2.|[2]Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4 (12) :a011148.|[3]Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res. 2006 Nov;26 (11) :827-33.