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Sucunamostat (hydrochloride)

Sucunamostat (SCO-792) hydrochloride is an orally active and reversible enteropeptidase inhibitor with IC50s of 4.6 nM and 5.4 nM for rat enteropeptidase and human enteropeptidase, respectively. Sucunamostat hydrochloride can slowly dissociate from enteropeptidase in vitro and inhibit protein digestion in vivo[1].

Product Specifications

Product Name Alternative

SCO-792 (hydrochloride)

UNSPSC

12352005

Target

Enteropeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sucunamostat-hydrochloride.html

Concentration

10mM

Purity

98.14

Solubility

DMSO : ≥ 125 mg/mL

Smiles

[H]Cl.OC(C[C@@H](C(O)=O)NC(C[C@H]1C2=CC=C(OC(C3=CC=C(C=C3)NC(N)=N)=O)C=C2OC1)=O)=O

Molecular Formula

C22H23ClN4O8

Molecular Weight

506.89

References & Citations

[1]Sasaki M, et al. Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792. Pharmacol Res Perspect. 2019 Sep 4;7 (5) :e00517.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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