Tos-PEG4-THP
Tos-PEG4-THP is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) [1].
Product Specifications
CAS Number
[86259-89-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tos-peg4-thp.html
Purity
95.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOC2CCCCO2)=O
Molecular Formula
C20H32O8S
Molecular Weight
432.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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