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Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Selected Variant

HY-148820-01

Size: 1 mg

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969[1].

Product Specifications

CAS Number

2857037-70-6

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/br-val-ala-nh2-bicyclo-1-1-1-pentane-7-mad-mdcpt.html

Purity

98.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

BrCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1)=O)=O)=O

Molecular Formula

C36H38BrN5O9

Molecular Weight

764.62

References & Citations

[1]Phillips AC, et, al. Anti-c-met antibody drug conjugates. WO2022232834A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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