Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969[1].
Product Specifications
CAS Number
[2857037-70-6]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/br-val-ala-nh2-bicyclo-1-1-1-pentane-7-mad-mdcpt.html
Purity
98.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
BrCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1)=O)=O)=O
Molecular Formula
C36H38BrN5O9
Molecular Weight
764.62
References & Citations
[1]Phillips AC, et, al. Anti-c-met antibody drug conjugates. WO2022232834A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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