(RS) -AMPA (hydrobromide)

(RS) -AMPA ((±) -AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS) -AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].

Product Specifications

CAS Number

[171259-81-7]

Product Name Alternative

(±) -AMPA (hydrobromide)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rs-ampa-hydrobromide.html

Purity

99.50

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)

Smiles

O=C1C(CC(N)C(O)=O)=C(C)ON1.Br

Molecular Formula

C7H11BrN2O4

Molecular Weight

267.08

Precautions

H302, H315, H319, H335

References & Citations

[1]Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36 (1) :59-62.|[2]Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249 (4976) :1580-5.