Thymidine-2′-13C
Product Specifications
UNSPSC Description
Thymidine-2′-13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]<
Target Antigen
DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Orthopoxvirus
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thymidine-2-13c.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C=C(C(N1)=O)C)[C@]2([H])O[C@@H]([C@H]([13CH2]2)O)CO
Molecular Weight
243.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17).;FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1150S5/Thymidine-2-13C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1150S5/
Clinical Information
No Development Reported
CAS Number
185553-96-2
Available Sizes
Curated Selection
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