2,7"-Phloroglucinol-6,6'-bieckol
2,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC50 values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research[1].
Product Specifications
CAS Number
[1621988-60-0]
UNSPSC
12352005
Target
Amylases; Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-7-phloroglucinol-6-6-bieckol.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(OC2=CC(O)=C3OC4=C(OC3=C2C5=C(C=C(C(OC6=C(OC7=CC(O)=CC(O)=C7)C(OC8=C(O)C=C(O)C=C8O)=C9)=C5OC6=C9O)O)O)C(O)=CC(O)=C4OC%10=CC(O)=CC(O)=C%10)=CC(O)=C1
Molecular Formula
C48H30O23
Molecular Weight
974.74
References & Citations
[1]Lee HA, et al. A phlorotannin constituent of Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice. Pharm Biol. 2017 Dec;55 (1) :1149-1154.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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