Human AK2 Protein (Highly Pure)

<strong>Human AK2 Protein (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2011558_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> AK2 protein (His tag), Purified recombinant Human AK2 protein, AK 2, AK-2, AK 2 protein, Adenylate kinase isoenzyme 2 protein, AK-2 protein, EC 2.7.4.3, AK2, ADK2 protein, Adenylate kinase 2 protein, ATP AMP transphosphorylase protein, AK2 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Cai F, Xu H, Zha D, Wang X, Li P, Yu S, Yao Y, Chang X, Chen J, Lu Y, Hua ZC, Zhuang H. AK2 Promotes the Migration and Invasion of Lung Adenocarcinoma by Activating TGF-β/Smad Pathway In vitro and In vivo Front Pharmacol. 2021 Sep 22;12:714365._x000D_ 2: Six E, Lagresle-Peyrou C, Susini S, De Chappedelaine C, Sigrist N, Sadek H, Chouteau M, Cagnard N, Fontenay M, Hermine O, Chomienne C, Reynier P, Fischer A, André-Schmutz I, Gueguen N, Cavazzana M. AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages Cell Death Dis. 2015 Aug 13;6(8):e1856._x000D_ 3: Stengel A, Baer C, Walter W, Meggendorfer M, Kern W, Haferlach T, Haferlach C. Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies Blood Adv. 2021 Nov 9;5(21):4426-4434._x000D_ 4: Chou J, Alazami AM, Jaber F, Hoyos-Bachiloglu R, Jones J, Weeks S, Alosaimi MF, Bainter W, Cangemi B, Badran YR, Mohammed R, Alroqi F, Almutairi A, Al-Onazi N, AlAjaji S, Al-Saud B, Arnaout R, Elkins M, Devana S, Imperial J, Li B, Drexhage L, Abdel Rahman AM, Jacob M, Haddad H, Hanna-Wakim R, Dbaibo G, Massaad MJ, Dasouki M, Mikhael R, Baz Z, Geha RS, Al-Mousa H. Hypomorphic variants in AK2 reveal the contribution of mitochondrial function to B-cell activation J Allergy Clin Immunol. 2020 Jul;146(1):192-202._x000D_ 5: Ye Y, Li M, Chen L, Li S, Quan Z. Circ-AK2 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-454-3p/THBS2 Placenta. 2021 Jan 1;103:156-163._x000D_ 6: Kim H, Jeong M, Na DH, Ryu SH, Jeong EI, Jung K, Kang J, Lee HJ, Sim T, Yu DY, Yu HC, Cho BH, Jung YK. AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis Cell Death Dis. 2022 May 18;13(5):469._x000D_ 7: Klein C. Congenital neutropenia Hematology Am Soc Hematol Educ Program. 2009:344-50._x000D_ 8: Zhao J, Xu J, Yang T, Yu X, Cheng C, Zhang T, Ren Z, Li N, Yang F, Li G. Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody BMC Biotechnol. 2021 Dec 20;21(1):71._x000D_ 9: Lee HJ, Pyo JO, Oh Y, Kim HJ, Hong SH, Jeon YJ, Kim H, Cho DH, Woo HN, Song S, Nam JH, Kim HJ, Kim KS, Jung YK. AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10 Nat Cell Biol. 2007 Nov;9(11):1303-10._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24548998">10: Kim H, Lee HJ, Oh Y, Choi SG, Hong SH, Kim HJ, Lee SY, Choi JW, Su Hwang D, Kim KS, Kim HJ, Zhang J, Youn HJ, Noh DY, Jung YK. The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth Nat Commun. 2014;5:3351. </a>_x000D_ _x000D_ <strong>Products Related to Human AK2 Protein (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>