Chrysoeriol

Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, IκB/p65, and NF-κB pathways, and has strong anti-inflammatory activity[1][2][3].

Product Specifications

CAS Number

[491-71-4]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/chrysoeriol.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=C(O)C(OC)=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C16H12O6

Molecular Weight

300.26

Precautions

H302, H312, H332

References & Citations

[1]Beena Mishra, et al. Effect of O-glycosilation on the Antioxidant Activity and Free Radical Reactions of a Plant Flavonoid, Chrysoeriol. Bioorg Med Chem. 2003 Jul 3;11 (13) :2677-85.|[2]Limboonreung T, et al. Chrysoeriol mediates mitochondrial protection via PI3K/Akt pathway in MPP+ treated SH-SY5Y cells. Neurosci Lett. 2020 Jan 1;714:134545.|[3]Wu JY, et al. Chrysoeriol ameliorates TPA-induced acute skin inflammation in mice and inhibits NF-κB and STAT3 pathways. Phytomedicine. 2020 Mar;68:153173.