TGP-377/421
TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 inhibitor that binds a functional site in both miRNAs[1].
Product Specifications
CAS Number
16752-89-9
Product Name Alternative
Targapre-miR-377/421
UNSPSC
12352005
Target
MicroRNA
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tgp-377-421.html
Purity
98.17
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
NC1=CC=C2C(N=C(C3=CC=CC(C4=NC5=CC(N)=CC=C5N4)=C3)N2)=C1
Molecular Formula
C20H16N6
Molecular Weight
340.38
References & Citations
[1]Haniff HS, et al. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions. Nat Chem. 2020 Oct;12 (10) :952-961.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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