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Piclozotan

Piclozotan (SUN N4057) is a 5HT1A receptor agonist. Piclozotan improves motor complications in Parkinson's disease model[1].

Product Specifications

CAS Number

182415-09-4

Product Name Alternative

SUN N4057

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/piclozotan.html

Smiles

O=C1C2=C(OC=C(N1CCCCN3CC=C(CC3)C4=CC=CC=N4)Cl)C=CC=C2

Molecular Formula

C23H24ClN3O2

Molecular Weight

409.91

References & Citations

[1]Tani Y, et al. Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats. Eur J Pharmacol. 2010 Dec 15;649 (1-3) :218-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

5-HT1 Receptor; mLAG-3

Frequently Asked Questions

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