Piclozotan
Piclozotan (SUN N4057) is a 5HT1A receptor agonist. Piclozotan improves motor complications in Parkinson's disease model[1].
Product Specifications
CAS Number
182415-09-4
Product Name Alternative
SUN N4057
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/piclozotan.html
Smiles
O=C1C2=C(OC=C(N1CCCCN3CC=C(CC3)C4=CC=CC=N4)Cl)C=CC=C2
Molecular Formula
C23H24ClN3O2
Molecular Weight
409.91
References & Citations
[1]Tani Y, et al. Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats. Eur J Pharmacol. 2010 Dec 15;649 (1-3) :218-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor; mLAG-3
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