N-Aminofluorescein
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu2+ in biological systems with λex/em=495/516 nm[1][2]. N-Aminofluorescein can be used to measure the concentration of copper ions in cells[3].
Product Specifications
CAS Number
98907-26-7
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n-aminofluorescein.html
Purity
99.91
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N(N)C2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=CC=C5
Molecular Formula
C20H14N2O4
Molecular Weight
346.34
References & Citations
[1]Chen X, et al. A selective fluorescence-on reaction of spiro form fluorescein hydrazide with Cu (II) . Anal Chim Acta. 2006 Aug 11;575 (2) :217-22. |[2]Uzra Diwan, et al. A water compatible turn ‘on’ optical probe for Cu2+ based on a fluorescein-sugar conjugate. Sensors and Actuators B: Chemical. 2014;196:345-351.|[3]Zhi HT, et al. Anticancer efficacy triggered by synergistically modulating the homeostasis of anions and iron: Design, synthesis and biological evaluation of dual-functional squaramide-hydroxamic acid conjugates. Bioorg Chem. 2024 Jun;147:107421.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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