PTZ601

PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671) -resistant Enterococcus faecium (VREF) and Methicillin (HY-121544) -resistant Staphylococcus aureus (MRSA) . PTZ601 exhibits antimicrobial activity in infected mouse models[1].

Product Specifications

CAS Number

[426253-04-5]

Product Name Alternative

Razupenem; SM 216601; SMP 601

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ptz601.html

Smiles

O=C(C(N12)=C(SC3=NC(C4=C[C@H](C)NC4)=CS3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O

Molecular Formula

C18H21N3O4S2

Molecular Weight

407.51

References & Citations

[1]Eguchi K, et al., Pharmacodynamics of SMP-601 (PTZ601) against vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus in neutropenic murine thigh infection models. Antimicrob Agents Chemother. 2009 Aug;53 (8) :3391-8.