BCOR (498-514), biotinylated
BCOR (498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR (498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells[1].
Product Specifications
UNSPSC
12352209
Target
BCL6
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcor-498-514-biotinylated.html
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N4[C@@H](CCC4)C(NCC(N5[C@@H](CCC5)C(N[C@@H](CCCCNC(CCCC[C@@H]6SC[C@]([C@]6([H])N7)([H])NC7=O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(NC(C)=O)=N)N
Molecular Formula
C98H155N25O29S
Molecular Weight
2179.49
References & Citations
[1]Ghetu AF, et al. Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer. Mol Cell. 2008 Feb 15;29 (3) :384-91.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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