Lisinopril (dihydrate)

Lisinopri dihydrate (MK-521 dihydrate) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

Product Specifications

CAS Number

[83915-83-7]

Product Name Alternative

MK-521 (dihydrate)

UNSPSC

12352005

Hazard Statement

H360, H373

Target

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Lisinopril-dihydrate.html

Purity

99.96

Solubility

DMSO : < 1 mg/mL|H2O : 20 mg/mL (ultrasonic)

Smiles

O=C(O)[C@H]1N(C([C@H](CCCCN)N[C@H](C(O)=O)CCC2=CC=CC=C2)=O)CCC1.O.O

Molecular Formula

C21H35N3O7

Molecular Weight

441.52

Precautions

H360, H373

References & Citations

[1]Andujar-Sanchez, M., V. Jara-Perez, and A. Camara-Artigas, Thermodynamic determination of the binding constants of angiotensin-converting enzyme inhibitors by a displacement method. FEBS Lett, 2007. 581 (18) : p. 3449-54.|[2]Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41 (3) : p. 207-24.