Toxin A from Clostridium difficile

<strong>Toxin A from Clostridium difficile</strong>_x000D_ <strong>Catalog number:</strong> B2017381_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> TcdA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A, Minton NP. The role of toxin A and toxin B in Clostridium difficile infection Nature. 2010 Oct 7;467(7316):711-3._x000D_ 2: Chandrasekaran R, Lacy DB. The role of toxins in Clostridium difficile infection FEMS Microbiol Rev. 2017 Nov 1;41(6):723-750._x000D_ 3: Aktories K, Papatheodorou P, Schwan C. Binary Clostridium_difficile toxin (CDT) - A virulence factor disturbing the cytoskeleton Anaerobe. 2018 Oct;53:21-29._x000D_ 4: Willing SE, Richards EJ, Sempere L, Dale AG, Cutting SM, Fairweather NF. Increased toxin expression in a Clostridium_difficile mfd mutant BMC Microbiol. 2015 Dec 18;15:280._x000D_ 5: Alvin JW, Lacy DB. Clostridium_difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue J Struct Biol. 2017 Jun;198(3):203-209._x000D_ 6: Drudy D, Fanning S, Kyne L. Toxin A-negative, toxin B-positive Clostridium_difficile Int J Infect Dis. 2007 Jan;11(1):5-10._x000D_ 7: Carter GP, Rood JI, Lyras D. The role of toxin_A and toxin_B in the virulence of Clostridium_difficile Trends Microbiol. 2012 Jan;20(1):21-9._x000D_ 8: Weiss K. Toxin-binding treatment for Clostridium difficile: a review including reports of studies with tolevamer Int J Antimicrob Agents. 2009 Jan;33(1):4-7._x000D_ 9: Fiorentini C, Thelestam M. Clostridium difficile_toxin_A and its effects on cells Toxicon. 1991;29(6):543-67._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25151204">10: Aldape MJ, Heeney DD, Bryant AE, Stevens DL. Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile J Antimicrob Chemother. 2015 Jan;70(1):153-9. </a>_x000D_ _x000D_ <strong>Products Related to Toxin A from Clostridium difficile can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>