SDZ 220-040

SDZ 220-040 is a competitive the mammalian NMDA receptor antagonist with a pKi of 8.5. SDZ 220-040 can be used in the study of neurological diseases[1][2].

Product Specifications

CAS Number

[174575-40-7]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sdz-220-040.html

Purity

99.14

Smiles

ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)(O)=O)=C2)O

Molecular Formula

C16H16Cl2NO6P

Molecular Weight

420.18

References & Citations

[1]Brian G Forde. et al. Glutamate signalling via a MEKK1 kinase-dependent pathway induces changes in Arabidopsis root architecture. Plant J. 2013 Jul;75 (1) :1-10. |[2]Urwyler S, et al. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35 (6) :655-69.