A63162
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA) -induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin -induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease[1].
Product Specifications
CAS Number
111525-11-2
UNSPSC
12352005
Target
Leukotriene Receptor; Lipoxygenase
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a63162.html
Smiles
CC(N(C(C)C1=CC=C(C=C1)OCC2=CC=CC=C2)O)=O
Molecular Formula
C17H19NO3
Molecular Weight
285.34
References & Citations
[1]Olsen S C, et al. Inhibition of equine mononuclear cell proliferation and leukotriene B4 synthesis by a specific 5-lipoxygenase inhibitor, A-63162[J]. American journal of veterinary research, 1992, 53 (6) : 1015-1018.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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