Ibuprofen guaiacol ester
Ibuprofen guaiacol ester (AF 2259; Metoxibutropate) is an orally active mutual prodrug of Ibuprofen and Guaiacol (HY-N1380), designed to reduce the gastrointestinal (GI) side effects of ibuprofen. Ibuprofen guaiacol ester inhibits the synthesis of prostaglandin. Ibuprofen guaiacol ester inherits the antipyretic, analgesic and anti-inflammatory properties of Ibuprofen and Guaiacol, but reduces gastric damage. Ibuprofen guaiacol ester can be used to alleviate gastric erosion/ulcers induced by classic anti-inflammatory agent (such as Ibuprofen)[2].
Product Specifications
CAS Number
66332-77-2
Product Name Alternative
Methoxybutropate; AF 2259; Metoxibutropate
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ibuprofen-guaiacol-ester.html
Purity
98.49
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(OC1=CC=CC=C1OC)C(C)C2=CC=C(CC(C)C)C=C2
Molecular Formula
C20H24O3
Molecular Weight
312.40
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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