MPX-007

MPX-007 is a GluN2A antagonist (IC50: 27 nM) . MPX-007 is a tools to probe GluN2A physiology, and to study neuropsychiatric and developmental disorders[1].

Product Specifications

CAS Number

[1688685-29-1]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mpx-007.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NCC1=CN=C(S1)C)C2=NC(C)=C(N=C2)CNS(=O)(C3=CC=C(C(F)=C3)F)=O

Molecular Formula

C18H17F2N5O3S2

Molecular Weight

453.49

References & Citations

[1]Volkmann RA, et al. MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit. PLoS One. 2016 Feb 1;11 (2) :e0148129.