Manool
Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G (2) /M phase of the cell cycle[1][2].
Product Specifications
CAS Number
[596-85-0]
UNSPSC
12352211
Hazard Statement
H315, H319, H335, H400
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/manool.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(CCC1)(C)[C@]([C@@]1(C)[C@H]2CC[C@](O)(C)C=C)([H])CCC2=C
Molecular Formula
C20H34O
Molecular Weight
290.48
Precautions
H315, H319, H335, H400
References & Citations
[1]de Oliveira PF, et al. Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells. Cytotechnology. 2016;68 (5) :2139-2143.|[2]Pratsinis H, et al. Antiproliferative activity of Greek propolis. J Med Food. 2010;13 (2) :286-290.|[3]Nicolella HD, et al. Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food Chem Toxicol. 2014;72:8-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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