O1918
O1918 is a selective non-CB1 receptor and GPR18 antagonist.
Product Specifications
CAS Number
536697-79-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/O1918.html
Concentration
34.91 mM * 1 mL in Methyl acetate
Purity
98.71
Solubility
10 mM in DMSO
Smiles
C=C([C@@H]1CCC(C)=C[C@H]1C2=C(OC)C=C(C)C=C2OC)C
Molecular Formula
C19H26O2
Molecular Weight
286.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Agnieszka Zakrzeska, et al. A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. Br J Pharmacol. 2010 Jun; 160 (3) : 574–584.|[2]Matouk AI, et al. Abnormal cannabidiol confers cardioprotection in diabetic rats independent of glycemic control. Eur J Pharmacol. 2018 Feb 5;820:256-264.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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