Aspartyl-alanyl-diketopiperazine
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].
Product Specifications
CAS Number
[110954-19-3]
Product Name Alternative
DA-DKP
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aspartyl-alanyl-diketopiperazine.html
Purity
98.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@@H](C(N[C@H]1C)=O)NC1=O
Molecular Formula
C7H10N2O4
Molecular Weight
186.17
References & Citations
[1]Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441 (1) :13-7.|[2]Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64 (1) :35-41.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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