EP 171
EP 171 is a TP receptor agonist and human platelet activator. EP 171 can induce constriction of guinea pig trachea, and the constriction can be inhibited by the TP receptor antagonist EP 092. EP 171 binds to TP receptors on intact human platelets with an IC50 of 2.9 nM[1].
Product Specifications
CAS Number
[122089-44-5]
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ep-171.html
Smiles
O=C(CCC/C=C\C[C@@H]1[C@H]([C@]2(CC[C@@]1(O2)[H])[H])/C=C/[C@@H](COC3=CC=C(C=C3)F)O)O
Molecular Formula
C23H29FO5
Molecular Weight
404.47
References & Citations
[1]EP 171: a high affinity thromboxane A2-mimetic, the actions of which are slowly reversed by receptor blockade
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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