WU-07047
WU-07047, a simplified analog of YM-254890 (HY-111557), is a selective Gαq/11 inhibitor. WU-07047 can inhibit nucleotide exchange[1].
Product Specifications
CAS Number
[1702378-78-6]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/wu-07047.html
Smiles
CC(C)[C@@H](O)[C@H](NC(C)=O)C(O[C@@H]([C@]1([H])NC(CCCCCCCNC([C@H](OC([C@H](C/C=C/COC1=O)NC(C)=O)=O)CC2=CC=CC=C2)=O)=O)C(C)C)=O
Molecular Formula
C39H58N4O11
Molecular Weight
758.90
References & Citations
[1]Derek T Rensing, et al. Toward the Selective Inhibition of G Proteins: Total Synthesis of a Simplified YM-254890 Analog. Org Lett. 2015 May 1;17 (9) :2270-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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