REDV (TFA)

REDV TFA is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV TFA can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1 (α4β1) . REDV TFA can be used for the research of cell adhesion[1].

Product Specifications

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/redv-tfa.html

Purity

99.81

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(O)=O)=O)=O)[C@H](CCCNC(N)=N)N.O=C(O)C(F)(F)F.[x]

Molecular Formula

C20H35N7O9.xC2HF3O2

Molecular Weight

517.53 (free acid)

References & Citations

[1]S P Massia, et al. Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin alpha 4 beta 1. J Biol Chem. 1992 Jul 15;267 (20) :14019-26.