GSK239512
GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD) [1].
Product Specifications
CAS Number
720691-69-0
UNSPSC
12352005
Hazard Statement
H301+H331
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk239512.html
Purity
99.09
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(C2=CC=C(OC3=CC=C4CCN(C5CCC5)CCC4=C3)N=C2)CCC1
Molecular Formula
C23H27N3O2
Molecular Weight
377.48
Precautions
H301+H331
References & Citations
[1]Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11 (1) :47-58.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
H3 Receptor
Available Sizes
Frequently Asked Questions
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