GSK239512

GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD) [1].

Product Specifications

CAS Number

[720691-69-0]

UNSPSC

12352005

Hazard Statement

H301+H331

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gsk239512.html

Purity

99.09

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N(C2=CC=C(OC3=CC=C4CCN(C5CCC5)CCC4=C3)N=C2)CCC1

Molecular Formula

C23H27N3O2

Molecular Weight

377.48

Precautions

H301+H331

References & Citations

[1]Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11 (1) :47-58.